Multiubiquitin chain assembly factor (E4); proteasome processivity factor that elongates polyUb chains on substrates, opposing Ubp6p, a branched polyubiquitin protease; required for retrograde transport of misfolded proteins during ERAD; required for ubiquitination of a subset of cytosolic misfolded proteins upon heat shock [Source:SGD;Acc:S000003109]

Chromosome VII: 238,353-241,085 forward strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 325 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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