Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex; required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1; similar to mammalian Acf1p, the regulatory subunit of the mammalian ATP-utilizing chromatin assembly and modifying factor (ACF) complex; ITC1 has a paralog, YPL216W, that arose from the whole genome duplication [Source:SGD;Acc:S000003101]
Chromosome VII: 257,707-261,501 forward strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 321 orthologues and 1 paralogue.