Saccharomyces cerevisiae (R64-1-1)
Description

Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; role in localizing Ypt7p to the vacuolar membrane; required for autophagy, the CVT pathway and mitophagy; potential Cdc28 substrate [Source:SGD;Acc:S000003092]

Synonyms

AUT12

Location

Chromosome VII: 274,780-276,714 reverse strand.

R64-1-1:BK006941.2

About this gene

This gene has 1 transcript (splice variant), 223 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
MON1YGL124C_mRNA1935644aaYGL124C
 
Protein coding
P53129 NM_001180989.2
NP_011391.2

Gene-based displays