Subunit of DUBm module of SAGA and SLIK; has roles in anchoring deubiquitination module (DUBm) into SAGA and SLIK complexes, maintaining organization and ubiquitin-binding conformation of Ubp8p, thereby contributing to overall DUBm activity; involved in preinitiation complex assembly at promoters; relocalizes to cytosol under hypoxia; human homolog ATXN7 implicated in spinocerebellar ataxia, and can complement yeast null mutant [Source:SGD;Acc:S000003034]
SCA7
Chromosome VII: 377,609-379,582 forward strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 59 orthologues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
SGF73 | YGL066W_mRNA | 1974 | 657aa | YGL066W | Protein coding | P53165 | - | Ensembl Canonical, |