Saccharomyces cerevisiae (R64-1-1)
Description

Nicotinamidase that converts nicotinamide to nicotinic acid; part of the NAD(+) salvage pathway; required for life span extension by calorie restriction; lacks a peroxisomal targeting signal but is imported into peroxisomes via binding to Gpd1p; PNC1 expression responds to all known stimuli that extend replicative life span; protein increases in abundance and relative distribution to cytoplasmic foci decreases upon DNA replication stress [Source:SGD;Acc:S000003005]

Location

Chromosome VII: 427,297-427,947 reverse strand.

R64-1-1:BK006941.2

About this gene

This gene has 1 transcript (splice variant), 177 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PNC1YGL037C_mRNA651216aaYGL037C
 
Protein coding
P53184 NM_001180902.3
NP_011478.3

Gene-based displays