Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog); regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway facilitates efficient Hac1p synthesis; two functional forms of Hac1p are produced; translation initiation is repressed under non-stress conditions; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001863]
ERN4, IRE15
Chromosome VI: 75,179-76,147 forward strand.
R64-1-1:BK006940.2
This gene has 1 transcript (splice variant), 18 orthologues and is a member of 1 Ensembl protein family.