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Saccharomyces cerevisiae (R64-1-1)
Description

Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; with Grx3p, binds to Aft1p in iron-replete conditions, promoting its dissociation from promoters; mutant has increased aneuploidy tolerance; transcription regulated by Yap5p; GRX4 has a paralog, GRX3, that arose from the whole genome duplication [Source:SGD;Acc:S000000976]

Location

Chromosome V: 538,434-539,168 reverse strand.

R64-1-1:BK006939.2

About this gene

This gene has 1 transcript (splice variant), 349 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
GRX4YER174C_mRNA735244aaYER174C
 
Protein coding
P32642 -Ensembl Canonical