Integral membrane protein of the ER; forms an ER-membrane associated protein complex with Slp1p; identified along with SLP1 in a screen for mutants defective in the unfolded protein response (UPR); proposed to function in the folding of integral membrane proteins; interacts genetically with MPS3; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000000942]
Chromosome V: 451,565-453,235 forward strand.
R64-1-1:BK006939.2
This gene has 1 transcript (splice variant), 342 orthologues and is a member of 1 Ensembl protein family.