Subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of the SEA complex, a coatomer-related complex that associates dynamically with the vacuole; Npr2p may have a structural or regulatory role, supporting Iml1p function as a GAP for the Rag family GTPase Gtr1p, and resulting in inhibition of TORC1 signaling in response to amino acid deprivation; SEACIT is required for non-nitrogen-starvation-induced autophagy; homolog of human tumor suppressor NPRL2 [Source:SGD;Acc:S000000788]
Chromosome V: 34,407-36,254 forward strand.
R64-1-1:BK006939.2
This gene has 1 transcript (splice variant) and 351 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
NPR2 | YEL062W_mRNA | 1848 | 615aa | YEL062W | Protein coding | P39923 | - | Ensembl Canonical, |