Translation elongation factor eIF-5A; required for translation of proteins containing polyproline stretches, including Bni1p, and this leads to a requirement for mating projection formation; structural homolog of bacterial EF-P; undergoes an essential hypusination modification; HYP2 has a paralog, ANB1, that arose from the whole genome duplication; human EIF5A complements the inviability of the yeast hyp2 anb1 double null mutant [Source:SGD;Acc:S000000760]

eIF-5A, eIF5A, TIF51A

Chromosome V: 85,676-86,149 forward strand.

R64-1-1:BK006939.2

This gene has 1 transcript (splice variant), 501 orthologues and 1 paralogue.

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