Saccharomyces cerevisiae (R64-1-1)
Description

Subunit of structure-specific Mms4p-Mus81p endonuclease; cleaves branched DNA; involved in DNA repair, replication fork stability, and joint molecule formation/resolution during meiotic recombination; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); helix-hairpin-helix protein; phosphorylation of non-catalytic subunit Mms4p by Cdc28p and Cdcp during mitotic cell cycle activates function of Mms4p-Mus81p [Source:SGD;Acc:S000002794]

Synonyms

SLX3

Location

Chromosome IV: 1,246,084-1,247,982 forward strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 395 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
MUS81YDR386W_mRNA1899632aaYDR386W
 
Protein coding
Q04149 NM_001180694.3
NP_010674.3

Gene-based displays