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Saccharomyces cerevisiae (R64-1-1)
Description

19S proteasome regulatory particle lid subcomplex component; role in Ub-dependent proteolysis and proteasome stability; involved in TREX-2 mediated mRNA export, and in the prevention of transcription-associated genome instability; ubiquitinated by Nedd4-like E3-ligase, Rsp5p; human ortholog DSS1, a BRCA1 binding protein implicated in cancer, complements the yeast null; drives trinucleotide repeat expansion; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000007235]

Synonyms

DSS1, HOD1

Location

Chromosome IV: 1,202,128-1,202,397 forward strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 25 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SEM1YDR363W-A_mRNA27089aaYDR363W-A
 
Protein coding
O94742 NM_001184328.3
NP_010651.3

Gene-based displays