Cytoplasmic thioredoxin reductase; key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress; protein abundance increases in response to DNA replication stress; TRR1 has a paralog, TRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000002761]

Chromosome IV: 1,183,299-1,184,258 forward strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 308 orthologues, 4 paralogues and is a member of 1 Ensembl protein family.

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