RING finger ubiquitin ligase (E3); involved in ubiquitination and degradation of excess histones; interacts with Ubc4p and Rad53p; null mutant sensitive to hydroxyurea (HU); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; computational analysis suggests a role as a transcription factor [Source:SGD;Acc:S000002674]
Chromosome IV: 1,000,104-1,002,023 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant) and 327 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
HEL2 | YDR266C_mRNA | 1920 | 639aa | YDR266C | Protein coding | Q05580 | - | Ensembl Canonical, |