SIR protein involved in assembly of silent chromatin domains; silent information regulator (SIR) along with SIR2 and SIR3; involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; some alleles of SIR4 prolong lifespan; required for telomere hypercluster formation in quiescent yeast cells [Source:SGD;Acc:S000002635]

ASD1, STE9, UTH2

Chromosome IV: 917,571-921,647 forward strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant) and 14 orthologues.

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