Catalytic epsilon subunit of the translation initiation factor eIF2B; eIF2B is the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000002619]
Chromosome IV: 884,727-886,865 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 335 orthologues and 2 paralogues.