Saccharomyces cerevisiae (R64-1-1)

Subunit of cohesin loading factor (Scc2p-Scc4p); a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; promotes gene expression program that supports translational fidelity; evolutionarily-conserved adherin; relocalizes to cytosol in response to hypoxia; human disorder Cornelia de Lange syndrome is caused by mutations in NIPBL, the human ortholog of SCC2 [Source:SGD;Acc:S000002588]


Chromosome IV: 821,295-825,776 forward strand.


About this gene

This gene has 1 transcript (splice variant) and 352 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
Q04002 -Ensembl Canonical