Saccharomyces cerevisiae (R64-1-1)

Translation termination factor eRF3; has a role in mRNA deadenylation and decay; altered protein conformation creates the [PSI(+)] prion that modifies cellular fitness, alters translational fidelity by affecting reading frame selection, and results in a nonsense suppressor phenotype; many stress-response genes are repressed in the presence of [PSI(+)] [Source:SGD;Acc:S000002579]

Gene Synonyms

eRF3, GST1, PNM2, SAL3, SUF12, SUP2, SUP36, [PSI(+)], [PSI]


Chromosome IV: 808,324-810,381 forward strand.


About this gene

This gene has 1 transcript (splice variant), 385 orthologues and 15 paralogues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P05453 -Ensembl Canonical