Subunit (61/68 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A; overexpression of the human ortholog, TAF12, an oncogene involved in the formation of choroid plexus carcinomas, results in dosage chromosomal instability (dCIN) in a human cell line similar to the dCIN observed in yeast overexpressors [Source:SGD;Acc:S000002552]
TAF61, TAF68, TafII61, TafII68
Chromosome IV: 746,738-748,357 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant) and 318 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
TAF12 | YDR145W_mRNA | 1620 | 539aa | YDR145W | Protein coding | Q03761 | - | Ensembl Canonical, |