Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions [Source:SGD;Acc:S000002488]
Chromosome IV: 607,304-610,081 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 136 orthologues and is a member of 1 Ensembl protein family.