Ubiquitin-conjugating enzyme (E2); catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation; protein abundance increases in response to DNA replication stress; human CDC34 functionally complements the thermosensitivity of the cdc34-2 mutant [Source:SGD;Acc:S000002461]

DNA6, UBC3

Chromosome IV: 561,440-562,327 reverse strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 268 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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