Uroporphyrinogen decarboxylase; catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; a hem12 mutant has phenotypes similar to patients with porphyria cutanea tarda [Source:SGD;Acc:S000002454]
HEM6
Chromosome IV: 551,860-552,948 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 351 orthologues, 6 paralogues and is a member of 2 Ensembl protein families.