RNA polymerase I termination factor; binds to rDNA terminator element, required for efficient Pol I termination; required for rDNA silencing at NTS1; facilities association of Sir2p with NTS1, contributes to rDNA stability and cell longevity; interacts physically with Fob1p and RENT subunits, Sir2p and Net1p; may interact with ribosomes, based on co-purification experiments; Myb-like DNA-binding protein; NSI1 has a paralog, REB1, that arose from the whole genome duplication [Source:SGD;Acc:S000002433]
Chromosome IV: 492,556-494,268 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 383 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
NSI1 | YDR026C_mRNA | 1713 | 570aa | YDR026C | Protein coding | Q12457 | NM_001180334.3 NP_010309.3 |