Saccharomyces cerevisiae (R64-1-1)
Description

Porphobilinogen deaminase; catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in heme biosynthesis; localizes to the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p, but not by levels of heme; human homolog HMBS can complement yeast mutant and allow growth of haploid null after sporulation of a heterozygous diploid [Source:SGD;Acc:S000002364]

Synonyms

OLE2

Location

Chromosome IV: 92,762-93,745 reverse strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 242 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
HEM3YDL205C_mRNA984327aaYDL205C
 
Protein coding
P28789 NM_001180265.1
NP_010076.1

Gene-based displays