Forms dehydrodolichyl diphosphate syntase complex with RER2 or SRT1; tet-repressible mutant shows accumulation of hypoglycosylated forms of CPY, suggesting that Nus1p may be involved in protein trafficking; mutations in human homolog NUS1 have been implicated in congenital scoliosis, neurological impairment, refractory epilepsy, hearing deficit, and visual impairment; human cis-prenyltransferase complex complements yeast null mutant [Source:SGD;Acc:S000002352]
Chromosome IV: 114,672-115,799 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant) and 323 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
NUS1 | YDL193W_mRNA | 1128 | 375aa | YDL193W | Protein coding | Q12063 | NM_001180253.1 NP_010088.1 |