Saccharomyces cerevisiae (R64-1-1)
Description

Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; dephosphorylates Tel1p/Mec1p-phosphorylated Cdc13p to promote telomerase release from telomeres at G2/M; PPH22 has a paralog, PPH21, that arose from the whole genome duplication [Source:SGD;Acc:S000002347]

Synonyms

PPH2

Location

Chromosome IV: 123,865-124,998 reverse strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 292 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PPH22YDL188C_mRNA1134377aaYDL188C
 
Protein coding
P23595 NM_001180248.1
NP_010093.1

Gene-based displays