RNA-binding subunit of the TRAMP nuclear RNA surveillance complex; involved in nuclear RNA processing and degradation; involved in TRAMP complex assembly as a bridge between Mtr4p and Trf4p; stimulates the poly(A) polymerase activity of Pap2p in vitro; has 5 zinc knuckle motifs; AIR2 has a paralog, AIR1, that arose from the whole genome duplication; Air2p and Air1p have nonredundant roles in regulation of substrate specificity of the exosome [Source:SGD;Acc:S000002334]

Chromosome IV: 144,484-145,518 reverse strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant) and 36 orthologues.

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