Cytoplasmic DEAD-box helicase, stimulates mRNA decapping; coordinates distinct steps in mRNA function and decay, interacting with both decapping and deadenylase complexes; role in translational repression, mRNA decay, and possibly mRNA export; interacts and cooperates with Ngr1p to promote specific mRNA decay; ATP- and RNA-bound form promotes processing body (PB) assembly, while ATPase stimulation by Not1p promotes PB disassembly; forms cytoplasmic foci on replication stress [Source:SGD;Acc:S000002319]
Chromosome IV: 170,410-171,930 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 375 orthologues, 26 paralogues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
DHH1 | YDL160C_mRNA | 1521 | 506aa | YDL160C | Protein coding | P39517 | - | Ensembl Canonical, |