Homocitrate synthase isozyme; catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; LYS21 has a paralog, LYS20, that arose from the whole genome duplication [Source:SGD;Acc:S000002289]

Chromosome IV: 227,393-228,715 forward strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 419 orthologues and 3 paralogues.

Show transcript tableHide transcript table