Homocitrate synthase isozyme; catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; LYS21 has a paralog, LYS20, that arose from the whole genome duplication [Source:SGD;Acc:S000002289]
Chromosome IV: 227,393-228,715 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 386 orthologues and 3 paralogues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
LYS21 | YDL131W_mRNA | 1323 | 440aa | YDL131W | Protein coding | Q12122 | NM_001180190.1 NP_010151.1 | Ensembl Canonical, |