RNA polymerase II transport factor, conserved from yeast to humans; also has a role in transporting RNA polymerase III into the nucleus; interacts with most of the RNAP II subunits; nucleo-cytoplasmic shuttling protein; deletion causes hypersensitivity to K1 killer toxin; protein increases in abundance and relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000002273]
Chromosome IV: 253,995-255,126 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 17 orthologues and is a member of 1 Ensembl protein family.