Protein involved in threonylcarbamoyl adenosine biosynthesis; Sua5p and Qri7p are necessary and sufficient for RNA t6A modification in vitro; highly conserved mitochondrial protein; essential for t6A modification of mitochondrial tRNAs that decode ANN codons; similar to Kae1p and E. coli YgjD, both of which are also required for tRNA t6A modification; when directed to the cytoplasm, complements the essential function of Kae1p in the KEOPS complex [Source:SGD;Acc:S000002262]

Chromosome IV: 273,653-274,876 reverse strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 327 orthologues and 1 paralogue.

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