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Saccharomyces cerevisiae (R64-1-1)
Description

Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; functions as a chaperone under ATP-depleted oxidative stress conditions; subunit of GET complex, involved in ATP dependent Golgi to ER trafficking and insertion of tail-anchored (TA) proteins into ER membrane under non-stress conditions; binds as dimer to transmembrane domain (TMD) cargo, shielding TMDs from aqueous solvent; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000002258]

Synonyms

ARR4

Location

Chromosome IV: 282,112-283,176 reverse strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 237 orthologues and is a member of 3 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
GET3YDL100C_mRNA1065354aaYDL100C
 
Protein coding
Q12154 NM_001180159.1
NP_010183.1

Gene-based displays