Saccharomyces cerevisiae (R64-1-1)
Description

Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; functions as a chaperone under ATP-depleted oxidative stress conditions; subunit of GET complex, involved in ATP dependent Golgi to ER trafficking and insertion of tail-anchored (TA) proteins into ER membrane under non-stress conditions; binds as dimer to transmembrane domain (TMD) cargo, shielding TMDs from aqueous solvent; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000002258]

Gene Synonyms

ARR4

Location

Chromosome IV: 282,112-283,176 reverse strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant) and 360 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
GET3YDL100C_mRNA1065354aaYDL100C
 
Protein coding
Q12154 -Ensembl Canonical