Saccharomyces cerevisiae (R64-1-1)
Description

NAD-dependent glycerol-3-phosphate dehydrogenase; key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; protein abundance increases in response to DNA replication stress; constitutively inactivated via phosphorylation by the protein kinases Ypk1p and Ypk2p, dephosphorylation increases catalytic activity; forms a heterodimer with Pnc1p to facilitate its peroxisomal import [Source:SGD;Acc:S000002180]

Synonyms

DAR1, HOR1, OSG1, OSR5

Location

Chromosome IV: 411,825-413,000 forward strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 321 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
GPD1YDL022W_mRNA1176391aaYDL022W
 
Protein coding
Q00055 NM_001180081.1
NP_010262.1

Gene-based displays