Saccharomyces cerevisiae (R64-1-1)
Description

Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex; role in Ub-mediated degradation of histone variant Cse4p preventing mislocalization to euchromatin; role in proteolysis of spindle positioning protein Kar9p, and DNA repair proteins Rad52p and Rad57p; forms SUMO-dependent nuclear foci, including DNA repair centers; contains a RING domain and two SIM motifs; associates with the centromere; required for maintenance of genome integrity like human ortholog RNF4 [Source:SGD;Acc:S000002171]

Synonyms

HEX3, ULS2

Location

Chromosome IV: 429,067-430,926 forward strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 55 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SLX5YDL013W_mRNA1860619aaYDL013W
 
Protein coding
P32828 NM_001180072.3
NP_010271.3

Gene-based displays