Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; contains a RING-H2 domain that is required for activity [Source:SGD;Acc:S000002166]
Chromosome IV: 433,497-433,994 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 259 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.