Subunit of the CCR4-NOT1 core complex; this complex has multiple roles in the regulation of mRNA levels including regulation of transcription and destabilization of mRNA by deadenylation; basal transcription factor that increases initiation and elongation; activates the ATPase activity of Dhh1p, resulting in processing body disassembly [Source:SGD;Acc:S000000689]
NOT1, ROS1, SMD6
Chromosome III: 280,117-286,443 forward strand.
R64-1-1:BK006937.2
This gene has 1 transcript (splice variant), 402 orthologues and is a member of 1 Ensembl protein family.