Integral ER membrane protein that stimulates Sar1p GTPase activity; involved in COPII vesicle budding through disassociation of coat proteins from membranes onto liposomes; binds Sec16p; SED4 has a paralog, SEC12, that arose from the whole genome duplication [Source:SGD;Acc:S000000663]
Chromosome III: 233,125-236,322 reverse strand.
R64-1-1:BK006937.2
This gene has 1 transcript (splice variant), 128 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.