Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway; ELO2 has a paralog, ELO1, that arose from the whole genome duplication; lethality of the elo2 elo3 double null mutation is functionally complemented by human ELOVL1 and weakly complemented by human ELOVL3 or ELOV7 [Source:SGD;Acc:S000000630]

Chromosome III: 190,592-191,635 forward strand.

R64-1-1:BK006937.2

This gene has 1 transcript (splice variant), 464 orthologues and 2 paralogues.

Show transcript tableHide transcript table