Saccharomyces cerevisiae (R64-1-1)
Description

S-phase checkpoint protein required for DNA replication; couples DNA helicase and polymerase; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; defines a novel S-phase checkpoint with Hog1p that coordinates DNA replication and transcription upon osmostress; protects uncapped telomeres; Dia2p-dependent degradation mediates checkpoint recovery; mammalian claspin homolog [Source:SGD;Acc:S000000566]

Synonyms

YCL060C

Location

Chromosome III: 18,816-22,106 reverse strand.

R64-1-1:BK006937.2

About this gene

This gene has 1 transcript (splice variant) and 306 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
MRC1YCL061C_mRNA32911096aaYCL061C
 
Protein coding
P25588 NM_001178704.1
NP_009871.2

Gene-based displays