Saccharomyces cerevisiae (R64-1-1)
Description

Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication [Source:SGD;Acc:S000000548]

Synonyms

MFP1, TRG1

Location

Chromosome III: 48,653-50,221 reverse strand.

R64-1-1:BK006937.2

About this gene

This gene has 1 transcript (splice variant), 330 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PDI1YCL043C_mRNA1569522aaYCL043C
 
Protein coding
P17967 NM_001178688.1
NP_009887.1

Gene-based displays