Glutathione-dependent disulfide oxidoreductase; hydroperoxide and superoxide-radical responsive, heat-stable, with active site cysteine pair; protects cells from oxidative damage; GRX1 has a paralog, GRX2, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000540]
Chromosome III: 60,841-61,173 reverse strand.
R64-1-1:BK006937.2
This gene has 1 transcript (splice variant), 235 orthologues, 3 paralogues and is a member of 2 Ensembl protein families.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
GRX1 | YCL035C_mRNA | 333 | 110aa | YCL035C | Protein coding | P25373 | NM_001178680.1 NP_009895.1 |