Saccharomyces cerevisiae (R64-1-1)

Guanine nucleotide exchange factor (GEF) for Cdc42p; activates Cdc42p in early G1, accounting for the first stage of biphasic activation, with Cdc24p accounting for the second stage in late G1; involved in the Cdc42p-mediated assembly of the axial landmark that dictates the site for the next round of budding, resulting in the axial budding pattern observed in haploids; localizes with septins to the bud neck contractile ring in mitosis [Source:SGD;Acc:S000000520]

Gene Synonyms



Chromosome III: 96,281-101,191 forward strand.


About this gene

This gene has 1 transcript (splice variant) and 33 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P25558 -Ensembl Canonical