Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins [Source:SGD;Acc:S000000506]
Chromosome II: 810,340-811,479 reverse strand.
This gene has 1 transcript (splice variant), 9 orthologues and 13 paralogues.
|Name||Transcript ID||bp||Protein||Translation ID||Biotype||UniProt||RefSeq||Flags|
|P0CX12 P0CX13||-||Ensembl Canonical,|