Third-largest subunit of DNA polymerase II (DNA polymerase epsilon); required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; stabilizes the interaction of Pol epsilon with primer-template DNA, positively affecting the processivity of the polymerase and exonuclease activities of Pol epsilon; mRNA abundance peaks at the G1/S boundary of the cell cycle; DPB3 has a paralog, DLS1, that arose from the whole genome duplication [Source:SGD;Acc:S000000482]

Chromosome II: 760,294-760,899 forward strand.

R64-1-1:BK006936.2

This gene has 1 transcript (splice variant), 216 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.

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