Deoxyuridine triphosphate diphosphatase (dUTPase); catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability; also has diphosphatase activity on deoxyinosine triphosphate; human homolog DUT allows growth of yeast haploid dut1 null mutant after sporulation of heterozygous diploid [Source:SGD;Acc:S000000456]
Chromosome II: 722,611-723,054 forward strand.
R64-1-1:BK006936.2
This gene has 1 transcript (splice variant) and 318 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
DUT1 | YBR252W_mRNA | 444 | 147aa | YBR252W | Protein coding | P33317 | - | Ensembl Canonical, |