Saccharomyces cerevisiae (R64-1-1)
Description

Methylesterase performing penultimate step of diphthamide biosynthesis; hydrolyzes methylated diphthine to produce diphthine and allows Dph6-catalyzed amidation reaction to occur; deletion leads to resistance to sordarin and accumulation of methylatediphthine; WD40 domain-containing protein; involved in endosomal recycling; forms complex with Rtt10p that functions in retromer-mediated pathway for recycling internalized cell-surface proteins [Source:SGD;Acc:S000000450]

Synonyms

ERE1

Location

Chromosome II: 711,591-712,754 forward strand.

R64-1-1:BK006936.2

About this gene

This gene has 1 transcript (splice variant), 230 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
RRT2YBR246W_mRNA1164387aaYBR246W
 
Protein coding
P38332 NM_001178594.1
NP_009805.1

Gene-based displays