Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation [Source:SGD;Acc:S000000421]

APG12

Chromosome II: 657,832-658,392 forward strand.

R64-1-1:BK006936.2

This gene has 1 transcript (splice variant), 331 orthologues and is a member of 1 Ensembl protein family.

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