Saccharomyces cerevisiae (R64-1-1)
Description

Cortical ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to the plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process [Source:SGD;Acc:S000000290]

Location

Chromosome II: 420,201-423,041 reverse strand.

R64-1-1:BK006936.2

About this gene

This gene has 1 transcript (splice variant), 355 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
IST2YBR086C_mRNA2841946aaYBR086C
 
Protein coding
P38250 NM_001178434.1
NP_009643.2

Gene-based displays