Saccharomyces cerevisiae (R64-1-1)
Description

5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; PRS4 has a paralog, PRS2, that arose from the whole genome duplication; a missense mutation in the conserved residue R196 of its human homolog PRPS1 is pathogenic [Source:SGD;Acc:S000000164]

Location

Chromosome II: 92,414-93,394 forward strand.

R64-1-1:BK006936.2

About this gene

This gene has 1 transcript (splice variant), 305 orthologues, 3 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PRS4YBL068W_mRNA981326aaYBL068W
 
Protein coding
P38063 NM_001178308.2
NP_009485.3

Gene-based displays