Saccharomyces cerevisiae (R64-1-1)
Description

S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase; methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; increases proportion of tRNALeu(CAA) with m5C at wobble position in response to hydrogen peroxide, causing selective translation of mRNA from genes enriched in TTG codon; loss of NCL1 confers hypersensitivity to oxidative stress; similar to Nop2p and human proliferation associated nucleolar protein p120 [Source:SGD;Acc:S000000120]

Synonyms

TRM4

Location

Chromosome II: 172,534-174,588 forward strand.

R64-1-1:BK006936.2

About this gene

This gene has 1 transcript (splice variant), 231 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
NCL1YBL024W_mRNA2055684aaYBL024W
 
Protein coding
P38205 NM_001178264.1
NP_009529.1

Gene-based displays